SCHEMBL10591024

SCHEMBL10591024

COC(=O)[C@H](Cc1ccccc1)NC(=O)CC(NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
ALOX15 P16050 1/20 0.62
CTSL P07711 1/20 0.57
CTSB P07858 1/20 0.57
CTSS P25774 1/20 0.57
CTSK P43235 1/20 0.57
KLK5 Q9Y337 1/20 0.55
CYP3A4 P08684 3/20 0.55
TSHR P16473 3/20 0.55
TACR1 P25103 2/20 0.55
KYNU Q16719 1/20 0.55
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089485 1.00 ALDH1A1 (0.62) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL8085158 0.92 ITGB3 (0.60) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL329686 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL7151822 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15CTSLCTSBCTSS
Hydrochloric Acid SCHEMBL7928050 0.88 ALDH1A1 (0.72) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL15070088 0.86 ALDH1A1 (0.66) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL2421066 0.86 ALDH1A1 (0.66) ALDH1A1ALOX15CTSLCTSBCTSS
SCHEMBL9615712 0.86 KLK5 (0.74) ALDH1A1CTSLCTSBCTSSCTSK
SCHEMBL8078197 0.85 ATM (0.53) ALDH1A1KLK5CYP3A4MEN1KMT2A
SCHEMBL9545976 0.85 CTSL (0.69) ALDH1A1ALOX15CTSLCTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333036-A2 Separation method of alpha-L-aspartyl-L-phenylalanine methyl ester MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-20 EP claimed