Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778048 | 0.85 | CYP4F2 (0.44) | ALOX15NPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL9778026 | 0.77 | ADRB2 (0.47) | NPC1SMN1; SMN2ADRB1ADRB3KDM4E | |
| SCHEMBL32672363 | 0.72 | BCAT2 (0.60) | BCAT2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22591171 | 0.72 | EPHX2 (0.42) | RAB9ASMN1; SMN2CA2LMNAEPHX2 | |
| SCHEMBL3982915 | 0.71 | MEN1 (0.56) | NPC1RAB9ASMN1; SMN2CA2KDM4E | |
| SCHEMBL4348072 | 0.71 | LMNA (0.55) | ALOX15RXRARXRBRXRGCA2 | |
| SCHEMBL9777978 | 0.70 | SLC7A5 (0.44) | BCAT2NPC1RAB9AADRB1ADRB3 | |
| SCHEMBL20289367 | 0.70 | HPGD (0.42) | RAB9ASMN1; SMN2LMNAEPHX2NR1H4 | |
| SCHEMBL2754731 | 0.70 | BCAT2 (0.42) | BCAT2NPC1RAB9ASMN1; SMN2ADRB1 | |
| SCHEMBL6896399 | 0.69 | CA2 (0.58) | CA2CAMK2AKDM4EAKR1B1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |