Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | G6PD | P11413 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 3/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL10454247 | 0.98 | INMT (0.38) | INMTKAT2BALDH1A1HPGDG6PD | |
| SCHEMBL8576689 | 0.90 | INMT (0.41) | INMTKAT2BALDH1A1HPGDG6PD | |
| SCHEMBL17863 | 0.85 | — | — | |
| Nitric Acid SCHEMBL14796686 | 0.82 | KAT2B (0.39) | INMTKAT2B | |
| SCHEMBL5712154 | 0.82 | INMT (0.41) | INMTKAT2BALDH1A1HPGDG6PD | |
| Hydrochloric Acid SCHEMBL11177863 | 0.81 | INMT (0.46) | INMTKAT2BALDH1A1HPGDG6PD | |
| Nitric Acid SCHEMBL9728066 | 0.72 | ALDH1A1 (0.79) | KAT2BALDH1A1HPGDG6PDALOX15 | |
| O-Xylene SCHEMBL27743854 | 0.61 | HSD17B10 (0.58) | ALDH1A1HSD17B10TSHRCA5ACA5B | |
| P-Xylene SCHEMBL9492886 | 0.60 | ACHE (0.62) | ALDH1A1HSD17B10CYP3A4TSHRCA5A | |
| Nitric Acid SCHEMBL28105440 | 0.60 | CA5A (0.50) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231505-B1 | ANTIMICROBIAL AGENT | Takeda Chemical Industries, Ltd. (JP) | 1989-09-27 | — | — | EP | claimed |