Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290528 | 0.73 | PDE3B (1.00) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL703687 | 0.71 | ALDH1A1 (0.60) | HPGDMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL2474844 | 0.71 | HPGD (0.70) | PDE3BPDE3AHPGDMEN1KMT2A | |
| SCHEMBL3556833 | 0.70 | ALDH1A1 (0.59) | HPGDCYP2C9CYP2C19ALDH1A1PTGS1 | |
| SCHEMBL14688925 | 0.70 | PIM1 (1.00) | PIM1ALOX15TSHRCYP2C19CYP3A4 | |
| SCHEMBL10149837 | 0.69 | ROCK1 (0.76) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL14699584 | 0.68 | MEN1 (0.50) | PDE3BPDE3APIM1MEN1KMT2A | |
| SCHEMBL7287713 | 0.68 | PDE3B (0.71) | PDE3BPDE3AMEN1KMT2AALOX15 | |
| SCHEMBL11144936 | 0.67 | HPGD (0.64) | HPGDMEN1KMT2AALOX15TSHR | |
| SCHEMBL10288495 | 0.67 | HPGD (0.64) | PDE3BPDE3AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1258671-A | — | — | None | — | — | JP | disclosed |
| JP-H01258671-A | 5-(1H-IMIDAZOL-1-YL)-3(2H)-PYRIDAZINONE DERIVATIVE | MORISHITA PHARMACEUT CO LTD | 1989-10-16 | — | — | JP | disclosed |