Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | FHIT | P49789 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535409 | 0.73 | CYP2A6 (0.62) | ALDH1A1GLAKDM4EHPGDHSD17B10 | |
| SCHEMBL9386148 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GLAKDM4EHPGDTSHR | |
| SCHEMBL8750126 | 0.71 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL5070273 | 0.71 | ALDH1A1 (0.61) | ALDH1A1GLAHPGDTSHRMAPT | |
| SCHEMBL13007252 | 0.70 | MCL1 (0.53) | ALDH1A1GLAKDM4EHPGDHSD17B10 | |
| SCHEMBL13061433 | 0.70 | MCL1 (0.53) | ALDH1A1GLAKDM4EHPGDHSD17B10 | |
| SCHEMBL31046010 | 0.69 | ALDH1A1 (0.59) | ALDH1A1GLAHPGDTSHRMAPT | |
| SCHEMBL939957 | 0.69 | ALDH1A1 (0.59) | ALDH1A1GLAHPGDTSHRMAPT | |
| SCHEMBL23271739 | 0.69 | ALDH1A1 (0.54) | ALDH1A1GLAHPGDTSHRMAPT | |
| SCHEMBL28564253 | 0.69 | ALDH1A1 (0.53) | ALDH1A1GLAHPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4435397-A | ADRENERGIC BLOCKING AGENTS, 4-(3-ARYLOXY-2-HYDROXYPROPYL) SUBSTITUTED | NIPPON SHINYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |