Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362853 | 0.84 | MAOB (0.59) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL8750157 | 0.82 | CTRC (0.48) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL8750122 | 0.82 | PON1 (0.49) | KDM4EALDH1A1GAAALOX15LMNA | |
| SCHEMBL19297000 | 0.81 | GPR55 (0.50) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL4750515 | 0.74 | CYP1A2 (0.43) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL30940063 | 0.72 | KMT2A (0.64) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL5904424 | 0.72 | KMT2A (0.64) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL8750107 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL10592991 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1MCL1CYP3A4GAA | |
| SCHEMBL15030960 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554074-B | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2015-03-25 | — | — | CN | claimed |
| CN-103554074-A | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2014-02-05 | — | — | CN | claimed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | claimed |
| US-20230286963-A1 | CHROMENONE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2023-09-14 | — | — | US | disclosed |
| CN-103554074-B | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2015-03-25 | — | — | CN | disclosed |
| CN-103554074-A | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2014-02-05 | — | — | CN | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-4441969-A | ARYL HYDROXY CARBOXYLIC ACID | OMI INTERNATIONAL CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286963-A1 | CHROMENONE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | CHRM1, CHRM2, CHRM3 | KDM4E 3371/4885ALDH1A1 1566/4885MCL1 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.