Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.59 |
| ▸ | AXL | P30530 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6647093 | 0.98 | NOS1 (0.57) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL10593107 | 0.84 | NOS1 (0.47) | NOS1AXLIDO1METAP2JAK2 | |
| Tert-Butyl Formate SCHEMBL27831645 | 0.81 | IDO1 (0.46) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL12601112 | 0.76 | NOS1 (0.61) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL16720263 | 0.75 | METAP2 (0.50) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL21437262 | 0.74 | NOS1 (0.44) | NOS1AXLIDO1METAP2CDK2 | |
| SCHEMBL18193497 | 0.74 | NOS1 (0.59) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL4314318 | 0.74 | NOS1 (1.00) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL907863 | 0.74 | NOS1 (0.59) | NOS1AXLIDO1METAP2JAK2 | |
| SCHEMBL5951586 | 0.74 | AXL (0.63) | NOS1AXLIDO1METAP2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105734586-B | A kind of organic-silicon-modified corrosion inhibitor and preparation method thereof | 中国石油化工股份有限公司 | 2018-04-10 | — | — | CN | claimed |
| CN-105734586-A | Organosilicon-modified corrosion inhibitor and preparation method thereof | 中国石油化工股份有限公司 | 2016-07-06 | — | — | CN | claimed |
| WO-2013086397-A1 | UREA COMPOUNDS AS GKA ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2013-06-13 | — | — | WO | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-4735425-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735440-A1 | KRAS INHIBITORS | Bristol-Myers Squibb Company (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYSOWAY THERAPEUTICS INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250248998-A1 | LRRK2 Inhibitors | Brenig Therapeutics, Inc. | 2025-08-07 | — | — | US | disclosed |
| EP-4540255-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| EP-4540254-A1 | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| EP-4504722-A2 | LRRK2 INHIBITORS | Brenig Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| US-4438128-A | ADRENERGIC BLOCKERS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | disclosed |
| EP-0042592-A1 | N-heteroarylalkylene diamines, process for their preparation and their use | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4168953-A | Oxidation hair dyes based upon tetraaminopyrimidine developers and monohydroxyindazole couplers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-09-25 | — | — | US | disclosed |
| US-4143149-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-06 | — | — | US | disclosed |
| US-3939084-A | Functional fluid compositions containing substituted pyrimidines | MONSANTO COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
| US-3931298-A | FROM A HYDROXYAROMATIC AND AMMONIA, GROUP 8-CYCLOHEXANONE CATALYST | ETHYL CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250248998-A1 | LRRK2 Inhibitors | LRRK2, PARK7, PINK1 | NOS1 3610/4885AXL 4268/4885IDO1 2676/4885 |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | STOML2, ATP2A3, ATP2A1 | NOS1 4223/4885AXL 2312/4885IDO1 4856/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | NOS1 2710/4885AXL 3140/4885IDO1 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.