Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 4/20 | 0.42 |
| ▸ | BRAF | P15056 | 4/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471094 | 0.86 | BRD4 (0.60) | BRD4KDM4EALDH1A1HPGDIDO1 | |
| SCHEMBL30425937 | 0.86 | BRD4 (0.60) | BRD4KDM4EALDH1A1HPGDIDO1 | |
| SCHEMBL12473426 | 0.78 | CA1 (0.55) | KDM4EALDH1A1HPGDIDO1PLAU | |
| SCHEMBL10595701 | 0.75 | ALDH1A1 (0.56) | BRD4KDM4EALDH1A1HPGDNOS1 | |
| SCHEMBL24861080 | 0.75 | ALDH1A1 (0.59) | BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL10593107 | 0.74 | NOS1 (0.47) | KDM4EALDH1A1HPGDIDO1ROCK2 | |
| SCHEMBL10596677 | 0.74 | TDP1 (0.48) | KDM4EALDH1A1HPGDIDO1ROCK2 | |
| SCHEMBL10595712 | 0.74 | NOS1 (0.72) | IDO1ROCK2ROCK1NOS1AXL | |
| SCHEMBL3537413 | 0.74 | BRD4 (0.48) | BRD4KDM4EALDH1A1HPGDIDO1 | |
| SCHEMBL23979717 | 0.73 | BRD4 (0.44) | BRD4KDM4EALDH1A1HPGDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |