Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244736 | 0.82 | DNM1 (0.52) | DNM1TSHRCA2LMNAFDPS | |
| SCHEMBL25676849 | 0.81 | — | — | |
| SCHEMBL28497518 | 0.80 | DNM1 (0.38) | ALDH1A1TDP1DNM1TSHRCYP3A4 | |
| SCHEMBL29244723 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL17495594 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL17421926 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL3020499 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL29244747 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL17422009 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS | |
| SCHEMBL2355127 | 0.79 | TSHR (0.50) | DNM1TSHRLMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546587-B2 | Method for producing acrylate derivative, acrylate derivative, and intermediate thereof | KURARAY CO., LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20130005990-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | KURARAY CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-8314258-B2 | Method for producing acrylate derivative, acrylate derivative, and intermediate thereof | KURARAY CO., LTD. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20110009643-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | KURARAY CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005990-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | ACR, ADH1A, ALAD | ALDH1A1 13/4885TDP1 2750/4885DNM1 4192/4885 |
| US-20110009643-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | ACR, ADH1A, ALAD | ALDH1A1 13/4885TDP1 2750/4885DNM1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.