Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594556 | 0.82 | NOS1 (0.58) | NOS1ALDH1A1MAPK1PARP1PRKCI | |
| SCHEMBL18398744 | 0.78 | KDM4E (0.47) | NOS1ALDH1A1MAPK1PARP1PRKCI | |
| SCHEMBL10594464 | 0.78 | TRPA1 (0.46) | NOS1ALDH1A1MAPK1PARP1PRKCI | |
| SCHEMBL11576985 | 0.72 | NOS1 (0.48) | NOS1METAP2TRPA1DYRK1AFGFR1 | |
| SCHEMBL276444 | 0.72 | HSD17B10 (0.53) | NOS1ALDH1A1MAPK1PARP1PRKCI | |
| SCHEMBL8761517 | 0.72 | HPRT1 (0.54) | NOS1ALDH1A1MAPK1PARP1PRKCI | |
| SCHEMBL10594265 | 0.72 | NOS1 (0.53) | NOS1METAP2TRPA1DYRK1AIDO1 | |
| SCHEMBL2702745 | 0.71 | MAPT (0.58) | NOS1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL4311223 | 0.70 | NOS1 (0.46) | NOS1MAPK1TRPA1CYP1A2 | |
| SCHEMBL28889099 | 0.69 | AHR (0.48) | ALDH1A1PARP1TRPA1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |