Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594268 | 0.82 | NOS1 (0.52) | NOS1TRPA1HSD17B10TDP1MAPK1 | |
| SCHEMBL10594553 | 0.74 | NOS1 (0.59) | NOS1TRPA1CHEK1FLT3PLK3 | |
| SCHEMBL104360 | 0.74 | NOS1 (1.00) | NOS1TRPA1CHEK1FLT3PLK3 | |
| SCHEMBL11576985 | 0.70 | NOS1 (0.48) | NOS1TRPA1CHEK1KMT2ADYRK1A | |
| SCHEMBL10595306 | 0.69 | MAPT (0.61) | NOS1MAPK10RIPK1KMT2APOLB | |
| SCHEMBL14911424 | 0.68 | NOS1 (0.56) | NOS1TRPA1CHEK1FLT3POLB | |
| SCHEMBL10594464 | 0.68 | TRPA1 (0.46) | NOS1TRPA1HSD17B10TDP1MAPK1 | |
| SCHEMBL18398744 | 0.68 | KDM4E (0.47) | NOS1CHEK1FLT3GAAKMT2A | |
| SCHEMBL204492 | 0.66 | NOS1 (0.53) | NOS1TRPA1CHEK1GAAKMT2A | |
| SCHEMBL276444 | 0.66 | HSD17B10 (0.53) | NOS1CHEK1FLT3KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |