Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.53 |
| ▸ | METAP2 | P50579 | 9/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594553 | 0.81 | NOS1 (0.59) | NOS1METAP2TRPA1IDO1AXL | |
| SCHEMBL10594461 | 0.78 | METAP2 (0.53) | NOS1METAP2TRPA1HSP90AA1IDO1 | |
| SCHEMBL18398743 | 0.77 | IDO1 (0.55) | NOS1METAP2HSP90AA1IDO1CDK2 | |
| SCHEMBL11578011 | 0.74 | NOS1 (0.48) | NOS1METAP2TRPA1TRPM8TRPV1 | |
| SCHEMBL14487466 | 0.74 | METAP2 (0.56) | NOS1METAP2IDO1DYRK1A | |
| SCHEMBL24131026 | 0.73 | METAP2 (0.51) | METAP2TRPA1IDO1 | |
| SCHEMBL24131138 | 0.73 | TRPA1 (0.50) | METAP2TRPA1IDO1CDK2 | |
| SCHEMBL10594268 | 0.72 | NOS1 (0.52) | NOS1METAP2TRPA1TRPM8TRPV1 | |
| SCHEMBL7572191 | 0.71 | NOS1 (0.50) | NOS1METAP2TRPA1IDO1AXL | |
| SCHEMBL16618130 | 0.71 | IDO1 (0.61) | NOS1METAP2IDO1AXLDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |