Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892543 | 1.00 | HPGD (0.50) | HPGDCES2CES1CA1CA2 | |
| SCHEMBL12810008 | 0.79 | SRD5A2 (0.51) | MAPTKMT2ARAB9AMEN1LMNA | |
| SCHEMBL1135097 | 0.76 | NPC1 (0.52) | MAPTKMT2ARAB9AMEN1LMNA | |
| SCHEMBL9418310 | 0.72 | RXFP1 (0.79) | HPGDCES2CES1CA1CA2 | |
| SCHEMBL51509 | 0.72 | RXFP1 (0.79) | HPGDCES2CES1CA1CA2 | |
| SCHEMBL2129171 | 0.69 | CA1 (0.87) | HPGDCES2CES1CA1CA2 | |
| SCHEMBL50261 | 0.69 | CES2 (0.77) | HPGDCES2CES1CA1CA2 | |
| SCHEMBL6618691 | 0.69 | CES2 (0.77) | HPGDCES2CES1CA1CA2 | |
| Benzophenone SCHEMBL27935236 | 0.69 | CES2 (0.77) | HPGDCES2CES1CA1CA2 | |
| Ethyne SCHEMBL8195983 | 0.68 | RXFP1 (0.73) | HPGDCES2CES1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530592-B2 | Catalyst components based on fulvene complexes | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2013-09-10 | — | — | US | disclosed |
| US-20110034653-A1 | Catalyst Components Based on Fulvene Complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-02-10 | — | — | US | disclosed |
| EP-2167518-B1 | CATALYST COMPONENTS BASED ON FULVENE COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2011-01-05 | — | — | EP | disclosed |
| EP-2167518-A2 | CATALYST COMPONENTS BASED ON FULVENE COMPLEXES | Total Petrochemicals Research Feluy (BE) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009013194-A2 | CATALYST COMPONENTS BASED ON FULVENE COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-29 | — | — | WO | disclosed |
| EP-2019111-A1 | Catalyst components based on fulvene complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034653-A1 | Catalyst Components Based on Fulvene Complexes | ESR1, ESR2, ETFB | HPGD 1996/4885CES2 2859/4885CES1 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.