Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595586 | 0.76 | LMNA (0.54) | ALDH1A1LMNAPTGS2 | |
| SCHEMBL4532460 | 0.73 | LMNA (0.44) | ALDH1A1TSHRLMNAMAPTHPGD | |
| SCHEMBL4961500 | 0.69 | LMNA (0.47) | LMNAMAPT | |
| SCHEMBL14394483 | 0.69 | LMNA (0.47) | LMNAPTGS2 | |
| SCHEMBL18107068 | 0.67 | LMNA (0.45) | LMNAPTGS2 | |
| SCHEMBL31069477 | 0.67 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL10595532 | 0.66 | LMNA (0.44) | ALDH1A1LMNAPTGS2NPC1MAPT | |
| SCHEMBL7104473 | 0.65 | ALOX15 (0.39) | ALDH1A1TSHRLMNANPC1 | |
| Hydrochloric Acid SCHEMBL10596067 | 0.65 | LMNA (0.43) | ALDH1A1LMNAPTGS2NPC1MAPT | |
| SCHEMBL5712065 | 0.64 | MGMT (0.50) | ALDH1A1LMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100081-B1 | PYRIDYL ALKYL NITRATE COMPOUND, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-01 | — | — | EP | claimed |
| US-4540701-A | 2-Nitroxymethyl and 2,6-bis-nitroxymethyl-pyridine compounds having vasodilating activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| EP-0100081-A2 | Pyridyl alkyl nitrate compound, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-08 | — | — | EP | claimed |
| EP-0100081-B1 | PYRIDYL ALKYL NITRATE COMPOUND, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4613608-A | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-23 | — | — | US | disclosed |
| US-4540701-A | 2-Nitroxymethyl and 2,6-bis-nitroxymethyl-pyridine compounds having vasodilating activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0100081-A2 | Pyridyl alkyl nitrate compound, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-08 | — | — | EP | disclosed |