Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379609 | 0.74 | MRGPRX4 (0.54) | ALOX15TSHRMRGPRX4LMNATDP1 | |
| SCHEMBL7104510 | 0.69 | ASPH (0.39) | ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL12861014 | 0.66 | MAOB (0.59) | ALDH1A1LMNAMAOBMAOAMAPK1 | |
| SCHEMBL4371245 | 0.66 | GRN (0.43) | — | |
| SCHEMBL26690039 | 0.65 | ALOX15 (0.52) | ALOX15TSHRHIF1AALDH1A1IGFBP3 | |
| SCHEMBL10596014 | 0.65 | ALDH1A1 (0.36) | TSHRALDH1A1NPC1LMNA | |
| SCHEMBL12861015 | 0.65 | MAOB (0.58) | ALDH1A1MRGPRX4MAOBMAOA | |
| SCHEMBL3867061 | 0.64 | CA12 (0.42) | TDP1 | |
| SCHEMBL25637880 | 0.63 | ALOX15 (0.78) | ALOX15TSHRHIF1AALDH1A1CA5A | |
| SCHEMBL26919214 | 0.62 | ALOX15 (0.47) | ALOX15TSHRHIF1AALDH1A1IGFBP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339665-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | Nicox S.A. (FR) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002030866-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | disclosed |