Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389794 | 0.77 | CDC25B (0.60) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL29380721 | 0.77 | IDO1 (0.73) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL419307 | 0.77 | IDO1 (0.73) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL4518755 | 0.76 | PLK1 (0.67) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL4469856 | 0.76 | CDC25B (0.78) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL7842295 | 0.76 | PLK1 (0.67) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL2949650 | 0.75 | PLK1 (0.57) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL3946697 | 0.75 | PLK1 (0.61) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL24101354 | 0.74 | PLK1 (0.70) | PLK1HPGDSCDC25BMAPTKMT2A | |
| SCHEMBL14537714 | 0.74 | HPGDS (0.58) | PLK1HPGDSCDC25BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171497-B1 | CATALYST SYSTEM AND PROCESS FOR POLYMERIZING CONJUGATED DIENES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |