Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416238 | 0.99 | SLC6A3 (0.40) | SLC6A3ALDH1A1TSHRTDP1POLB | |
| SCHEMBL9765187 | 0.84 | SLC6A3 (0.41) | SLC6A3ALDH1A1TSHRTDP1POLB | |
| SCHEMBL10414984 | 0.84 | KMT2A (0.38) | SLC6A3ALDH1A1TDP1POLBMAPT | |
| SCHEMBL10786741 | 0.82 | PPOX (0.38) | — | |
| SCHEMBL10414982 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10599013 | 0.81 | PPOX (0.34) | ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL10416239 | 0.81 | SLC6A3 (0.40) | SLC6A3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10455217 | 0.81 | PPOX (0.38) | — | |
| SCHEMBL10414863 | 0.80 | PPOX (0.34) | ALDH1A1TSHRTDP1MAPTHTT | |
| SCHEMBL10716545 | 0.74 | MAPT (0.36) | ALDH1A1MAPTHTTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142648-B1 | 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3 DIONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-03-08 | — | — | EP | claimed |
| US-4595409-A | Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1986-06-17 | — | — | US | claimed |
| EP-0142648-A1 | 2-Substituted phenyl-4,5,6,7-tetrahydro-2h-isoindole-1,3 diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-05-29 | — | — | EP | claimed |