Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414986 | 0.84 | RAB9A (0.39) | SLC6A3PPOXKDM4EALDH1A1 | |
| SCHEMBL10416238 | 0.82 | SLC6A3 (0.40) | SLC6A3ALDH1A1HPGD | |
| SCHEMBL10596296 | 0.81 | SLC6A3 (0.42) | SLC6A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10414983 | 0.81 | PPOX (0.41) | PPOXALDH1A1 | |
| SCHEMBL10843729 | 0.81 | PPOX (0.42) | PPOX | |
| SCHEMBL9765187 | 0.79 | SLC6A3 (0.41) | SLC6A3ALDH1A1CASP3 | |
| SCHEMBL9737192 | 0.77 | PPOX (0.44) | PPOX | |
| SCHEMBL10907628 | 0.73 | KDM4E (0.36) | SLC6A3CYP19A1KDM4EALDH1A1HPGD | |
| SCHEMBL10644384 | 0.73 | SLC6A3 (0.40) | SLC6A3PPOX | |
| SCHEMBL10907441 | 0.72 | KDM4E (0.38) | SLC6A3CYP19A1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902832-A | 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-20 | — | — | US | disclosed |