SCHEMBL10596609

SCHEMBL10596609

NC(CCP(=O)(O)c1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.62
POLB P06746 1/20 0.60
KMT2A Q03164 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CFTR P13569 1/20 0.60
GRM4 Q14833 5/20 0.50
GRM8 O00222 4/20 0.50
GRM7 Q14831 2/20 0.50
GLUL P15104 1/20 0.50
GRM6 O15303 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27724080 0.79 GLUL (0.54) POLBKMT2ATDP1GRM4GRM8
SCHEMBL806049 0.77 CFTR (1.00) ALDH1A1KMT2ATDP1CFTR
SCHEMBL25332244 0.77 ALDH1A1 (1.00) ALDH1A1KMT2ACFTR
SCHEMBL2038461 0.76 KMT2A (1.00) ALDH1A1POLBKMT2ATDP1
SCHEMBL7607497 0.76 FOLH1 (0.60) ALDH1A1CFTR
SCHEMBL6767415 0.75 ALDH1A1 (0.77) ALDH1A1KMT2ACFTR
SCHEMBL14287993 0.74 CFTR (0.75) ALDH1A1POLBKMT2ACFTR
SCHEMBL56342 0.73 POLB (0.50) POLBKMT2ATDP1GRM4GRM8
SCHEMBL14287997 0.73 CFTR (0.82) ALDH1A1POLBKMT2ATDP1CFTR
SCHEMBL1969235 0.73 GLUL (0.70) GRM4GRM8GRM7GLULGRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127429-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE ((3-AMINO-3-CARBOXY)PROPYL-1) PHOSPHINIC ACID DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 1989-04-19 EP disclosed
EP-0085391-B1 PHOSPHINIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1986-01-15 EP disclosed
US-4510102-A FUNGICIDE;HERBICIDES;ALKYLALKYLPHOSPHONYL HALIDE STARTING MATERIAL MEIJI SEIKA KAISHA LTD. (JP) 1985-04-09 US disclosed
US-4499027-A REACTING A SHIFF'S BASE AND AN ALKYL VINYL PHOSPHINATE USING A BASIC CATALYST; HYDROLYSIS; STEREOSPECIFIC MEIJI SEIKA KAISHA, LTD. (JP) 1985-02-12 US disclosed
EP-0127429-A2 Process for preparing optically active ((3-amino-3-carboxy)propyl-1) phosphinic acid derivatives MEIJI SEIKA KAISHA LTD. (JP) 1984-12-05 EP disclosed
EP-0085391-A1 Phosphinic acid derivatives and process for preparing the same MEIJI SEIKA KAISHA LTD. (JP) 1983-08-10 EP disclosed