SCHEMBL10598784

SCHEMBL10598784

CC(C)C[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)[C](Cc1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602514 0.89 REN (0.53) REN
SCHEMBL10598636 0.89 REN (0.53) REN
SCHEMBL11041696 0.89 REN (0.62) REN
SCHEMBL10601098 0.86 REN (0.57) REN
SCHEMBL10597992 0.84 REN (0.49) REN
SCHEMBL11039196 0.84 REN (0.50) REN
SCHEMBL11039111 0.84 REN (0.55) REN
SCHEMBL10598154 0.83 REN (0.52) REN
SCHEMBL10598050 0.82 REN (0.52) REN
SCHEMBL10603723 0.82 REN (0.48) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0081783-B2 RENIN INHIBITORY PEPTIDES HAVING PHE 13 DELETION MERCK & CO. INC. (US) 1989-02-08 — — EP claimed
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