Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033547 | 1.00 | PTGER4 (0.53) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL24075642 | 0.82 | PTGER4 (0.56) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL3128231 | 0.79 | NFE2L2 (0.43) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL3128239 | 0.79 | NFE2L2 (0.43) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL23527384 | 0.79 | CYP1A2 (0.60) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL23527383 | 0.79 | CYP1A2 (0.60) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL11875055 | 0.78 | GABRA1 (0.44) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL15106904 | 0.78 | PTGER4 (0.51) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL6546776 | 0.78 | PTGER4 (0.56) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL1932534 | 0.78 | ALDH1A1 (0.55) | PTGER4PTGER3PTGER2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696620-B2 | Antimicrobial compounds | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20180290963-A1 | ANTIMICROBIAL COMPOUNDS | BOULOS, RAMIZ (AU) | 2018-10-11 | — | — | US | disclosed |
| US-9738591-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2017-08-22 | — | — | US | disclosed |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2017-02-02 | — | — | US | disclosed |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2015-07-09 | — | — | US | disclosed |
| US-9023892-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2015-05-05 | — | — | US | disclosed |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2012-12-27 | — | — | US | disclosed |
| WO-2011075766-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180290963-A1 | ANTIMICROBIAL COMPOUNDS | MRPL21, SPOUT1, MPO | PTGER4 4282/4885PTGER3 4490/4885PTGER2 4316/4885 |
| US-10696620-B2 | Antimicrobial compounds | MRPL21, SPOUT1, MPO | PTGER4 4282/4885PTGER3 4490/4885PTGER2 4316/4885 |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | PTGER4 4438/4885PTGER3 4593/4885PTGER2 4377/4885 |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | MRPL21, SPOUT1, MPO | PTGER4 4282/4885PTGER3 4490/4885PTGER2 4316/4885 |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | PTGER4 4438/4885PTGER3 4593/4885PTGER2 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.