Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.55 |
| ▸ | BLM | P54132 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.48 |
| ▸ | THPO | P40225 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270905 | 0.84 | TDP1 (0.58) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL30268632 | 0.84 | TDP1 (0.58) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL10039785 | 0.84 | TDP1 (0.58) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL7270873 | 0.84 | TDP1 (0.58) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL19422383 | 0.82 | TDP1 (0.60) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL17385607 | 0.81 | ADRB2 (0.57) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL10763030 | 0.80 | TDP1 (0.54) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL10763032 | 0.80 | TDP1 (0.54) | TDP1BLMLMNANR1I2PTGS1 | |
| SCHEMBL10778817 | 0.79 | LMNA (0.42) | TDP1LMNAKDM4EMAPTCYP1A2 | |
| SCHEMBL10778827 | 0.79 | LMNA (0.42) | TDP1LMNAKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141613-B1 | A PROCESS FOR PRODUCING AN OPTICALLY ACTIVE 3-(3,4-DIHYDROXPHENYL) SERINE AND A PROTECED DERIVATIVE THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-02-01 | — | — | EP | claimed |
| US-9920342-B2 | Process for the preparation of Droxidopa | DIVI'S LABORATORIES LIMITED | 2018-03-20 | — | — | US | disclosed |
| US-20170335357-A1 | PROCESS FOR THE PREPARATION OF DROXIDOPA | DIVI'S LABORATORIES LIMITED (IN) | 2017-11-23 | — | — | US | disclosed |
| US-4699879-A | ENZYMIC DEACYLATION | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0141613-A2 | A process for producing an optically active 3-(3,4-dihydroxphenyl) serine and a proteced derivative thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170335357-A1 | PROCESS FOR THE PREPARATION OF DROXIDOPA | DAO, DDO, DNPEP | TDP1 2816/4885BLM 4884/4885LMNA 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.