Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 12/20 | 0.58 |
| ▸ | BLM | P54132 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.54 |
| ▸ | THPO | P40225 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039785 | 1.00 | TDP1 (0.58) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL30268632 | 1.00 | TDP1 (0.58) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL7270905 | 1.00 | TDP1 (0.58) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL19422383 | 0.85 | TDP1 (0.60) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL17385607 | 0.84 | ADRB2 (0.57) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL9335039 | 0.84 | TDP1 (0.47) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL7272826 | 0.84 | TDP1 (0.47) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL10600115 | 0.84 | TDP1 (0.55) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL10763030 | 0.83 | TDP1 (0.54) | TDP1BLMLMNAADRA1ANR1I2 | |
| SCHEMBL10763032 | 0.83 | TDP1 (0.54) | TDP1BLMLMNAADRA1ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218440-A2 | N-Methylphenylserine alkyl ester derivatives and uses thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-04-15 | — | — | EP | claimed |
| EP-0112606-A1 | Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-07-04 | — | — | EP | claimed |
| JP-59112914-A | — | — | None | — | — | JP | disclosed |
| JP-62077358-A | — | — | None | — | — | JP | disclosed |
| JP-58225044-A | — | — | None | — | — | JP | disclosed |
| US-10654890-B2 | Cyclic peptide derivative, method for preparing same and composition thereof | BIOCOCOON LABORATORIES, INC. (JP) | 2020-05-19 | — | — | US | disclosed |
| US-20190085027-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PREPARING SAME AND COMPOSITION THEREOF | NATIONAL UNIVERSITY CORPORATION, IWATE UNIVERSITY (JP) | 2019-03-21 | — | — | US | disclosed |
| US-20170291921-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PREPARING SAME AND COMPOSITION THEREOF | NATIONAL UNIVERSITY CORPORATION, IWATE UNIVERSITY (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170291921-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PREPARING SAME AND COMPOSITION THEREOF | NATIONAL UNIVERSITY CORPORATION, IWATE UNIVERSITY (JP) | 2017-10-12 | — | — | US | disclosed |
| US-5288898-A | Alpha-adrenergic and beta-adrenergic agents to stimulate central nervous system | ZAIDAN HOJIM BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-02-22 | — | — | US | disclosed |
| US-4833268-A | PARKINSON*S DISEASE, ANTIDEPRESSANTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0141613-B1 | A PROCESS FOR PRODUCING AN OPTICALLY ACTIVE 3-(3,4-DIHYDROXPHENYL) SERINE AND A PROTECED DERIVATIVE THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-02-01 | — | — | EP | disclosed |
| US-4699879-A | ENZYMIC DEACYLATION | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0218440-A2 | N-Methylphenylserine alkyl ester derivatives and uses thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-04-15 | — | — | EP | disclosed |
| JP-S6277358-A | N-METHYLPHENYLSERINE DERIVATIVE | MICROBIAL CHEM RES FOUND | 1987-04-09 | — | — | JP | disclosed |
| EP-0141613-A2 | A process for producing an optically active 3-(3,4-dihydroxphenyl) serine and a proteced derivative thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-05-15 | — | — | EP | disclosed |
| EP-0112606-A1 | Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-07-04 | — | — | EP | disclosed |
| JP-S59112914-A | DRUG FOR PARKINSON'S DISEASE AND ANTIDEPRESSANT | MICROBIAL CHEM RES FOUND | 1984-06-29 | — | — | JP | disclosed |
| JP-S58225044-A | NOVEL 3-(3,4-DIHYDROXYPHENYL)SERINE DERIVATIVE AND PREPARATION THEREOF | MICROBIAL CHEM RES FOUND | 1983-12-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085027-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PREPARING SAME AND COMPOSITION THEREOF | NGLY1, VIP, BDNF | TDP1 2783/4885BLM 4257/4885LMNA 3796/4885 |
| US-10654890-B2 | Cyclic peptide derivative, method for preparing same and composition thereof | NGLY1, VIP, BDNF | TDP1 2783/4885BLM 4257/4885LMNA 3796/4885 |
| US-20170291921-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PREPARING SAME AND COMPOSITION THEREOF | NGLY1, VIP, BDNF | TDP1 2783/4885BLM 4257/4885LMNA 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.