Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.55 |
| ▸ | BLM | P54132 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.55 |
| ▸ | THPO | P40225 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30268632 | 0.84 | TDP1 (0.58) | ADRB2PTGS2TDP1BLMLMNA | |
| SCHEMBL10039785 | 0.84 | TDP1 (0.58) | ADRB2PTGS2TDP1BLMLMNA | |
| SCHEMBL7270873 | 0.84 | TDP1 (0.58) | ADRB2PTGS2TDP1BLMLMNA | |
| SCHEMBL7270905 | 0.84 | TDP1 (0.58) | ADRB2PTGS2TDP1BLMLMNA | |
| SCHEMBL19422383 | 0.82 | TDP1 (0.60) | ADRB2PTGS2OPRK1SLC6A3TDP1 | |
| SCHEMBL10600115 | 0.81 | TDP1 (0.55) | ADRB2PTGS2OPRK1SLC6A3TDP1 | |
| SCHEMBL10763030 | 0.80 | TDP1 (0.54) | ADRB2PTGS2OPRK1SLC6A3TDP1 | |
| SCHEMBL10763032 | 0.80 | TDP1 (0.54) | ADRB2PTGS2OPRK1SLC6A3TDP1 | |
| SCHEMBL10805909 | 0.79 | ADRA1A (0.54) | ADRB2PTGS2OPRK1SLC6A3TDP1 | |
| SCHEMBL13957303 | 0.78 | ADRA2C (0.48) | TDP1LMNAADRA1AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2962687-B1 | TAU AGGREGATION INHIBITOR | THE DOSHISHA (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-9907799-B2 | Tau aggregation inhibitor | THE DOSHISHA (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20160030437-A1 | TAU AGGREGATION INHIBITOR | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2016-02-04 | — | — | US | disclosed |
| EP-2962687-A1 | TAU AGGREGATION INHIBITOR | The Doshisha (JP) | 2016-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160030437-A1 | TAU AGGREGATION INHIBITOR | MAPT, PSEN2, PSEN1 | ADRB2 825/4885PTGS2 2578/4885OPRK1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.