Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | S100A4 | P26447 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600354 | 1.00 | TLR9 (0.78) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL13389949 | 1.00 | TLR9 (0.78) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL2578234 | 0.88 | TLR9 (1.00) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL2578236 | 0.88 | TLR9 (1.00) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL10826101 | 0.84 | TLR9 (0.82) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL10825882 | 0.84 | TLR9 (0.82) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL343050 | 0.81 | TLR9 (0.70) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL25428935 | 0.80 | TLR9 (0.50) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL10791359 | 0.80 | TSHR (0.50) | TLR9ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL19518780 | 0.80 | TLR9 (0.50) | TLR9ALDH1A1MAPTTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158002-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MYELODYSPLASTIC SYNDROMES AND/OR ACUTE MYELOID LEUKEMIAS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2023-05-25 | — | — | US | disclosed |
| US-20170233788-A1 | Cysteine Labelling | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2017-08-17 | — | — | US | disclosed |
| CN-106890114-A | Topical compositions comprising Pichia anomala and chicory root extract | 强生消费者公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-103260706-B | Composition comprising panlownin and/or Paulownia extract and application thereof | 强生消费者公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106692029-A | Topical gel cream composition | 强生消费者公司 | 2017-05-24 | — | — | CN | disclosed |
| US-9302988-B2 | Fluoromethyl-substituted pyrrole carboxamides | Grünenthal GmbH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20140066426-A1 | FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES | GRUENENTHAL GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8268845-B2 | Tetrahydro- and dihydroquinazolinones | MERCK PATENT GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20090318444-A1 | TETRAHYDRO- AND DIHYDROQUINAZOLINONES | MERCK PATENT GMBH (DE) | 2009-12-24 | — | — | US | disclosed |
| EP-0104863-B1 | LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158002-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MYELODYSPLASTIC SYNDROMES AND/OR ACUTE MYELOID LEUKEMIAS | MCL1, HMBS, HPGDS | TLR9 3541/4885ALDH1A1 772/4885MAPT 4507/4885 |
| US-20140066426-A1 | FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES | TRPV1, CACNA1B, CACNA1G | TLR9 3105/4885ALDH1A1 3161/4885MAPT 1147/4885 |
| US-20090318444-A1 | TETRAHYDRO- AND DIHYDROQUINAZOLINONES | CSNK1A1, MAP3K19, DMPK | TLR9 4251/4885ALDH1A1 2043/4885MAPT 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.