Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578236 | 0.82 | TLR9 (1.00) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL2578234 | 0.82 | TLR9 (1.00) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL13389949 | 0.81 | TLR9 (0.78) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL10600352 | 0.81 | TLR9 (0.78) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL10600354 | 0.81 | TLR9 (0.78) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL6585727 | 0.80 | TLR9 (0.70) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL10825882 | 0.78 | TLR9 (0.82) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL15108575 | 0.78 | TLR9 (0.67) | TLR9GAAALDH1A1MAPTTDP1 | |
| SCHEMBL758697 | 0.78 | CA2 (0.50) | TLR9GAACA1CA2CA12 | |
| SCHEMBL9752512 | 0.78 | TSHR (0.54) | TLR9GAAALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805168-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-110835310-B | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114805168-A | Pyrrolinone compound and synthetic method thereof | 百顺药业有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-110835352-B | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2022-05-24 | — | — | CN | claimed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | claimed |
| US-10117864-B2 | Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | claimed |
| US-20180036300-A1 | SUBSTITUTED N-BICYCLO-2-ARYL-QUINOLIN-4-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-08 | — | — | US | claimed |
| EP-3271334-A1 | SUBSTITUTED N-BICYCLO-2-ARYL-QUINOLIN-4-CARBOXAMIDES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-24 | — | — | EP | claimed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | claimed |
| WO-2017153235-A1 | SUBSTITUTED N-CYCLO-3-ARYL-1-NAPHTHAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | WO | claimed |
| US-20060074113-A1 | Thiadiazoline derivative | KYOWA KIRIN CO., LTD. (JP) | 2006-04-06 | — | — | US | claimed |
| EP-1455900-A1 | METHODS OF TREATING BACTERIAL INFECTIONS IN DOGS AND CATS | Pfizer Products Inc. (US) | 2004-09-15 | — | — | EP | claimed |
| EP-1454903-A1 | THIADIAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-08 | — | — | EP | claimed |
| US-20030149013-A1 | Methods of treating bacterial infections in dogs and cats | PFIZER PRODUCTS INC. | 2003-08-07 | — | — | US | claimed |
| WO-2003053522-A1 | METHODS OF TREATING BACTERIAL INFECTIONS IN DOGS AND CATS | PFIZER PRODUCTS INC. (US) | 2003-07-03 | — | — | WO | claimed |
| EP-0725783-B1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-12-18 | — | — | EP | claimed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| US-4477662-A | 2-Substituted thio carbapenem derivatives | BEECHAM GROUP P.L.C. (GB) | 1984-10-16 | — | — | US | claimed |
| US-3953437-A | Process of preparing cephalosporanic acid ester derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-3935198-A | BY HEATING THE PENICILLIN SULFOXIDE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074113-A1 | Thiadiazoline derivative | BRWD1, RB1, ARG2 | TLR9 2930/4885GAA 4130/4885ALDH1A1 343/4885 |
| US-20030149013-A1 | Methods of treating bacterial infections in dogs and cats | CAT, PIGO, IL1B | TLR9 732/4885GAA 104/4885ALDH1A1 272/4885 |
| US-10117864-B2 | Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof | AADAC, BRD4, GOT2 | TLR9 613/4885GAA 861/4885ALDH1A1 1711/4885 |
| US-20180036300-A1 | SUBSTITUTED N-BICYCLO-2-ARYL-QUINOLIN-4-CARBOXAMIDES AND USE THEREOF | AADAC, BRD4, GOT2 | TLR9 613/4885GAA 861/4885ALDH1A1 1711/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | TLR9 386/4885GAA 1797/4885ALDH1A1 1582/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | TLR9 386/4885GAA 1797/4885ALDH1A1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.