Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872575 | 0.78 | KMT2A (0.50) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL9754754 | 0.75 | CA1 (0.50) | TGM2CA1CA12MMP2MMP9 | |
| SCHEMBL6269067 | 0.75 | CA1 (0.54) | TGM2CA1CA12MMP2MMP9 | |
| SCHEMBL6269658 | 0.75 | TGM2 (0.54) | TGM2CA1CA12MMP2MMP9 | |
| SCHEMBL1102071 | 0.71 | KMT2A (0.71) | TGM2MEN1KMT2ATSHRGAA | |
| Hydrochloric Acid SCHEMBL5967288 | 0.70 | CA12 (0.51) | TGM2CA1CA12MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL27491393 | 0.70 | KMT2A (0.69) | TGM2MEN1KMT2ATSHRGAA | |
| SCHEMBL10917178 | 0.69 | TDP1 (0.42) | TGM2MEN1KMT2ATSHRGAA | |
| SCHEMBL3164409 | 0.68 | ALDH1A1 (0.59) | MEN1KMT2ATSHRGAAALDH1A1 | |
| SCHEMBL8956995 | 0.68 | TSHR (0.38) | MEN1KMT2ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150765-B1 | USE OF P-UREIDOALKYLAMINO NITROBENZENE COMPOUNDS IN HAIR DYEING COMPOSITIONS AND P-UREIDOALKYLAMINO NITROBENZENE COMPOUNDS | Wella Aktiengesellschaft (DE) | 1989-03-22 | — | — | EP | claimed |
| US-4629467-A | HIGH INTENSITY ALKALI RESISTANCE; YELLOW COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | claimed |
| US-4629467-A | HIGH INTENSITY ALKALI RESISTANCE; YELLOW COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| US-4629467-A | HIGH INTENSITY ALKALI RESISTANCE; YELLOW COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| WO-1985003223-A1 | UTILIZATION OF COMPOUNDS OF p-UREIDOALKYLAMINO-NITROBENZENE IN HAIR COLORANTS AND NEW COMPOUNDS OF p-UREIDOALKYLAMINO-NITROBENZENE | WELLA AKTIENGESELLSCHAFT (DE) | 1985-08-01 | — | — | WO | disclosed |