Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429351 | 0.82 | CA12 (0.48) | TGM2CA12CA1MMP2MMP9 | |
| SCHEMBL6269067 | 0.79 | CA1 (0.54) | TGM2CA12CA1MMP2MMP9 | |
| SCHEMBL5539582 | 0.78 | TGM2 (0.47) | TGM2CA12MEN1KMT2AHPGD | |
| SCHEMBL14935791 | 0.76 | CA12 (0.54) | TGM2CA12CA1MMP2MMP9 | |
| SCHEMBL9754754 | 0.76 | CA1 (0.50) | TGM2CA12CA1MMP2MMP9 | |
| SCHEMBL515915 | 0.76 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL8373371 | 0.76 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL515914 | 0.76 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL2034750 | 0.76 | CA12 (0.54) | TGM2CA12CA1MMP2MMP9 | |
| SCHEMBL10600425 | 0.75 | TGM2 (0.50) | TGM2CA12CA1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |