SCHEMBL10600445

SCHEMBL10600445

Cc1cccc(NC(=O)C(C)OCc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
TP53 P04637 2/20 0.59
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
MAPT P10636 3/20 0.54
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
LRRK2 Q5S007 1/20 0.51
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 1/20 0.50
MAPK1 P28482 1/20 0.50
TSHR P16473 1/20 0.49
CCKBR P32239 1/20 0.48
CTSK P43235 1/20 0.48
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598199 0.92 ALDH1A1 (0.53) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL10555782 0.87 LTA4H (0.56) ALDH1A1KMT2AMEN1MAPTNPC1
SCHEMBL17833423 0.86 ALDH1A1 (0.57) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL13555325 0.78 LTA4H (0.48) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL14336343 0.78 LTA4H (0.48) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL5853166 0.78 MGLL (0.72) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL12310044 0.76 LMNA (0.65) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL28555017 0.76 ALDH1A1 (0.65) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL26463800 0.76 ALDH1A1 (0.65) ALDH1A1TP53KMT2AMEN1MAPT
SCHEMBL28555016 0.76 ALDH1A1 (0.65) ALDH1A1TP53KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP claimed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US claimed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP claimed
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP disclosed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US disclosed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP disclosed