SCHEMBL10600533

SCHEMBL10600533

CCCCC(CC)CN(Cn1ccnn1)Cn1ccnn1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570383 0.97 ALDH1A1 (0.36) ALDH1A1CYP3A4TSHRTDP1L3MBTL1
SCHEMBL10600908 0.76 CYP19A1 (0.35) CYP19A1
SCHEMBL10600715 0.73 DNM1 (0.33) CYP19A1
SCHEMBL1605802 0.73 DNM1 (0.33) CYP19A1
SCHEMBL27995274 0.72 LMNA (0.37) CYP19A1
SCHEMBL18723226 0.72 TBXAS1 (0.35) CYP19A1
SCHEMBL10605553 0.71 CYP19A1 (0.38) ALDH1A1CYP19A1
SCHEMBL19529565 0.71 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRTDP1L3MBTL1
SCHEMBL18400707 0.71 LMNA (0.36) ALDH1A1CYP19A1
SCHEMBL166842 0.71 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0160620-B1 METAL DEACTIVATORS CIBA-GEIGY AG (CH) 1989-09-13 EP claimed