Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602221 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11436048 | 0.74 | GPR84 (0.34) | — | |
| SCHEMBL11442855 | 0.73 | ACE2 (0.31) | PDCD4 | |
| SCHEMBL11439627 | 0.72 | ACE2 (0.31) | — | |
| SCHEMBL11448440 | 0.71 | ACE2 (0.33) | — | |
| SCHEMBL11435133 | 0.71 | FFAR4 (0.30) | — | |
| SCHEMBL9537327 | 0.69 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL21461234 | 0.64 | GPR84 (0.45) | ALDH1A1 | |
| SCHEMBL11442814 | 0.64 | PRKCA (0.32) | — | |
| SCHEMBL3388101 | 0.63 | ALDH1A1 (0.55) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175325-B1 | NEW 8-SUBSTITUTED NUCLEOSIDE AND PURINE DERIVATIVES, THE PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pierrel S.p.A. (IT) | 1989-03-15 | — | — | EP | disclosed |
| US-4774325-A | ANTILIPEMIC AGENTS | PIERREL SPA (IT) | 1988-09-27 | — | — | US | disclosed |
| EP-0175325-A2 | New 8-substituted nucleoside and purine derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them | Pierrel S.p.A. (IT) | 1986-03-26 | — | — | EP | disclosed |