Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23789 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL3514310 | 0.82 | MAPT (0.52) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL23456361 | 0.81 | PKM (0.53) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL6233037 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EMAPK1KMT2A | |
| SCHEMBL4553218 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL453875 | 0.80 | GPR35 (0.56) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL10600910 | 0.77 | GLA (0.48) | ALDH1A1MAPTGPR35KDM4EMAPK1 | |
| SCHEMBL14364287 | 0.75 | MAPT (0.60) | ALDH1A1MAPTKDM4EMAPK1KMT2A | |
| SCHEMBL4807504 | 0.75 | GPR35 (0.53) | ALDH1A1MAPTGPR35KMT2AMEN1 | |
| SCHEMBL14944070 | 0.75 | MAPT (0.49) | ALDH1A1MAPTGPR35KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151400-B1 | HAIR DYEING COMPOSITIONS WITH PICRAMIC ACID DERIVATIVES, NEW PICRAMIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Wella Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | claimed |
| EP-0151400-A2 | Hair dyeing compositions with picramic acid derivatives, new picramic acid derivatives and process for preparing same | Wella Aktiengesellschaft (DE) | 1985-08-14 | — | — | EP | claimed |
| WO-1985003222-A1 | HAIR COLORANT WITH PICRAMIC ACID DERIVATIVES, NEW PICRAMIC ACID DERIVATIVES AND PRODUCTION PROCESS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 1985-08-01 | — | — | WO | claimed |
| EP-0151400-B1 | HAIR DYEING COMPOSITIONS WITH PICRAMIC ACID DERIVATIVES, NEW PICRAMIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Wella Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0151400-A2 | Hair dyeing compositions with picramic acid derivatives, new picramic acid derivatives and process for preparing same | Wella Aktiengesellschaft (DE) | 1985-08-14 | — | — | EP | disclosed |