Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23789 | 0.89 | ALDH1A1 (0.53) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL4553218 | 0.89 | ALDH1A1 (0.54) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL29410422 | 0.88 | ALDH1A1 (0.63) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL24055 | 0.88 | ALDH1A1 (0.63) | PKMALDH1A1TDP1TSHRKMT2A | |
| Bromide SCHEMBL28440810 | 0.87 | ALDH1A1 (0.62) | PKMALDH1A1TDP1TSHRKMT2A | |
| 3-Nitro-Phenol SCHEMBL7120003 | 0.84 | PKM (0.67) | PKMALDH1A1TDP1TSHRKMT2A | |
| Methoxymethane SCHEMBL7085872 | 0.83 | ALDH1A1 (0.58) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL563763 | 0.82 | PKM (0.67) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL6001854 | 0.82 | TDP1 (0.56) | PKMALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL10601066 | 0.81 | ALDH1A1 (0.51) | PKMALDH1A1TDP1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029808-B2 | Kit and method for dyeing keratinous material by means of aminosilicone and a chromophoric compound | HENKEL AG & CO. KGAA (DE) | 2024-07-09 | — | — | US | disclosed |
| US-20240207160-A1 | PROCESS OF COLORING KERATINOUS MATERIAL COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN EFFECT PIGMENT, AND A SEALING REAGENT VI | HENKEL AG & CO. KGAA (DE) | 2024-06-27 | — | — | US | disclosed |
| US-11992546-B2 | Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent vi | HENKEL AG & CO. KGAA (US) | 2024-05-28 | — | — | US | disclosed |
| US-11957779-B2 | Agent for dyeing keratinous material, containing aminosilicone, pigment and polysaccharide | HENKEL AG & CO. KGAA (US) | 2024-04-16 | — | — | US | disclosed |
| US-11957771-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a coated effect pigment and a sealing reagent I | HENKEL AG & CO. KGAA (US) | 2024-04-16 | — | — | US | disclosed |
| US-11938211-B2 | Process for coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, a further coloring compound and a film-forming polymer I | HENKEL AG & CO. KGAA (DE) | 2024-03-26 | — | — | US | disclosed |
| US-11918665-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a colored effect pigment and a sealing reagent I | HENKEL AG & CO. KGAA (US) | 2024-03-05 | — | — | US | disclosed |
| US-20240041741-A1 | COSMETIC COMPOSITION OBTAINED BY MIXING TWO SILANE BLENDS | HENKEL AG & CO. KGAA (DE) | 2024-02-08 | — | — | US | disclosed |
| US-11883522-B2 | Agent for dyeing keratinous material, containing aminosilicone, a chromophoric compound and phosphorous-containing surfactant | HENKEL AG & CO. KGAA (DE) | 2024-01-30 | — | — | US | disclosed |
| US-11878071-B2 | Product for dyeing keratinous material, containing aminosilicone, a chromophoric compound, preservative and a fatty constituent | HENKEL AG & CO. KGAA (DE) | 2024-01-23 | — | — | US | disclosed |
| US-20220054395-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, CONTAINING DYE AND AN ACIDIC POST-TREATMENT AGENT | HENKEL AG & CO. KGAA (DE) | 2022-02-24 | — | — | US | disclosed |
| US-20220000749-A1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | HENKEL AG & CO. KGAA (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20220000751-A1 | METHOD FOR PREPARING AND USING HAIR TREATMENT AGENTS WITH ORGANIC C1-C6-ALKOXY-SILANES | HENKEL AG & CO. KGAA (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20220000750-A1 | THE PROCESS FOR THE PREPARATION AND USE OF HAIR TREATMENT COMPOSITIONS CONTAINING ORGANIC C1-C6 ALKOXY SILANES | HENKEL AG & CO. KGAA (DE) | 2022-01-06 | — | — | US | disclosed |
| US-20210401712-A1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | HENKEL AG & CO. KGAA (DE) | 2021-12-30 | — | — | US | disclosed |
| US-20210212916-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN OLIGOALKYLSILOXANE AND A DYEING COMPOUND | HENKEL AG & CO. KGAA (DE) | 2021-07-15 | — | — | US | disclosed |
| US-20210196616-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A SILICON OIL | HENKEL AG & CO. KGAA (DE) | 2021-07-01 | — | — | US | disclosed |
| US-20210186841-A1 | HAIR DYE COMPOSITION CONTAINING AT LEAST ONE ORGANIC SILICON COMPOUND, A DIRECT DYE AND A FILM FORMING HYDROPHOBIC POLYMER | HENKEL AG & CO. KGAA (DE) | 2021-06-24 | — | — | US | disclosed |
| US-20210169755-A1 | DUST REDUCED AMMONIUM FREE BLONDING POWDER | HENKEL AG & CO. KGAA (DE) | 2021-06-10 | — | — | US | disclosed |
| US-20210169762-A1 | AMMONIA-FREE BLEACHING KIT FOR GENTLE BRIGHTENING OF KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992546-B2 | Process of coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, and a sealing reagent vi | KRT18, VIM, MSH6 | PKM 1737/4885ALDH1A1 653/4885TDP1 3840/4885 |
| US-20240041741-A1 | COSMETIC COMPOSITION OBTAINED BY MIXING TWO SILANE BLENDS | KRT18, ALG3, H1-0 | PKM 2652/4885ALDH1A1 547/4885TDP1 3507/4885 |
| US-20220054395-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, CONTAINING DYE AND AN ACIDIC POST-TREATMENT AGENT | KRT18, CUTA, MARK1 | PKM 694/4885ALDH1A1 581/4885TDP1 3063/4885 |
| US-20240207160-A1 | PROCESS OF COLORING KERATINOUS MATERIAL COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN EFFECT PIGMENT, AND A SEALING REAGENT VI | KRT18, GP6, MSH6 | PKM 1262/4885ALDH1A1 826/4885TDP1 3734/4885 |
| US-12029808-B2 | Kit and method for dyeing keratinous material by means of aminosilicone and a chromophoric compound | MARK1, KRT18, KIT | PKM 813/4885ALDH1A1 1854/4885TDP1 2841/4885 |
| US-20210196616-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A SILICON OIL | KRT18, MKI67, DSG1 | PKM 788/4885ALDH1A1 2126/4885TDP1 4127/4885 |
| US-20220000749-A1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | KRT18, CUTA, INHA | PKM 3232/4885ALDH1A1 367/4885TDP1 2803/4885 |
| US-11938211-B2 | Process for coloring keratinous material comprising the use of an organosilicon compound, an effect pigment, a further coloring compound and a film-forming polymer I | KRT18, PKN1, CUTA | PKM 479/4885ALDH1A1 712/4885TDP1 2573/4885 |
| US-20210212916-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN OLIGOALKYLSILOXANE AND A DYEING COMPOUND | KRT18, MKI67, PCNA | PKM 1517/4885ALDH1A1 384/4885TDP1 2995/4885 |
| US-20220000750-A1 | THE PROCESS FOR THE PREPARATION AND USE OF HAIR TREATMENT COMPOSITIONS CONTAINING ORGANIC C1-C6 ALKOXY SILANES | KRT18, AKR1C3, C9 | PKM 1458/4885ALDH1A1 37/4885TDP1 3953/4885 |
| US-11918665-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a colored effect pigment and a sealing reagent I | KRT18, EPCAM, DSG1 | PKM 1830/4885ALDH1A1 259/4885TDP1 3535/4885 |
| US-11878071-B2 | Product for dyeing keratinous material, containing aminosilicone, a chromophoric compound, preservative and a fatty constituent | FABP4, APMAP, KRT18 | PKM 149/4885ALDH1A1 1508/4885TDP1 4188/4885 |
| US-11957771-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a coated effect pigment and a sealing reagent I | KRT18, EPCAM, JUP | PKM 1207/4885ALDH1A1 225/4885TDP1 3462/4885 |
| US-20220000751-A1 | METHOD FOR PREPARING AND USING HAIR TREATMENT AGENTS WITH ORGANIC C1-C6-ALKOXY-SILANES | POLR1C, ADH1C, AKR1C3 | PKM 2642/4885ALDH1A1 34/4885TDP1 3782/4885 |
| US-20210186841-A1 | HAIR DYE COMPOSITION CONTAINING AT LEAST ONE ORGANIC SILICON COMPOUND, A DIRECT DYE AND A FILM FORMING HYDROPHOBIC POLYMER | KRT18, DSG1, CUTA | PKM 1651/4885ALDH1A1 354/4885TDP1 2947/4885 |
| US-20210401712-A1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | KRT18, INHA, BUB1 | PKM 2585/4885ALDH1A1 1080/4885TDP1 2332/4885 |
| US-11883522-B2 | Agent for dyeing keratinous material, containing aminosilicone, a chromophoric compound and phosphorous-containing surfactant | KRT18, PHOSPHO1, PHYKPL | PKM 951/4885ALDH1A1 3908/4885TDP1 2780/4885 |
| US-11957779-B2 | Agent for dyeing keratinous material, containing aminosilicone, pigment and polysaccharide | KRT18, ALG3, ARSA | PKM 793/4885ALDH1A1 2035/4885TDP1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.