SCHEMBL10604103

SCHEMBL10604103

C=C[Si](CCl)(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BCL2A1 Q16548 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602162 0.79 BCL2A1 (0.31) BCL2A1
SCHEMBL1271103 0.78 ALDH1A1 (0.33)
SCHEMBL10600481 0.72 NR1H2 (0.33)
SCHEMBL29214127 0.70 TGM2 (0.34)
SCHEMBL22563443 0.70 TGM2 (0.34)
SCHEMBL29214126 0.70 TGM2 (0.39)
SCHEMBL11013983 0.69 CYP19A1 (0.47)
SCHEMBL10598734 0.69 IDO1 (0.33)
SCHEMBL10952579 0.69 IDO1 (0.33)
SCHEMBL9229806 0.69 IDO1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148026-B1 FUNGICIDAL IMIDAZOLES AND TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-19 EP disclosed
US-4530922-A Fungicidal imidazoles and triazoles containing silicon E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-23 US disclosed
EP-0148026-A2 Fungicidal imidazoles and triazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-10 EP disclosed