SCHEMBL1060422

SCHEMBL1060422

C=C[Si](C)(C)Oc1cccc(O[Si](C)(C)C=C)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 1/20 0.32
ACHE P22303 1/20 0.31
CYP3A4 P08684 3/20 0.31
TP53 P04637 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TSHR P16473 1/20 0.31
HIF1A Q16665 1/20 0.31
CHRM5 P08912 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
MITF O75030 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12798754 0.94 TDP1 (0.41) ALDH1A1TDP1LMNASMN1; SMN2MEN1
SCHEMBL1322780 0.87 CYP3A4 (0.50) ALDH1A1HPGDCYP3A4TP53SMN1; SMN2
SCHEMBL21086727 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8150674 0.84 CA4 (0.39) ALDH1A1TSHRMEN1KMT2A
SCHEMBL1060011 0.81 ALDH1A1 (0.32) ALDH1A1CYP3A4TP53SMN1; SMN2TSHR
SCHEMBL13326877 0.78 ALDH1A1 (0.38) ALDH1A1HPGDTDP1LMNASMN1; SMN2
SCHEMBL12798757 0.74 NPC1 (0.40) ALDH1A1SMN1; SMN2MEN1KMT2AMITF
SCHEMBL19547985 0.74 ACHE (0.41) ALDH1A1HPGDTDP1LMNAACHE
SCHEMBL3901324 0.74 LMNA (0.38) ALDH1A1HPGDTDP1LMNAACHE
SCHEMBL3716473 0.74 CYP1A1 (0.50) LMNACYP3A4TP53SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116367-A1 POLYBUTADIENE AND METHOD FOR PRODUCING SAME 宇部興産株式会社 2020-06-11 WO disclosed
US-8637225-B2 Magnetic recording medium and magnetic recording/reproducing apparatus SHOWA DENKO K.K. (JP) 2014-01-28 US disclosed
US-20130307195-A1 CURABLE COMPOSITION FOR TRANSFER MATERIALS AND METHOD FOR FORMING MICROPATTERN USING THE CURABLE COMPOSITION SHOWA DENKO K.K. (JP) 2013-11-21 US disclosed
US-20110129689-A2 CURABLE COMPOSITION FOR TRANSFER MATERIALS AND METHOD FOR FORMING MICROPATTERN USING THE CURABLE COMPOSITION SHOWA DENKO K.K. (JP) 2011-06-02 US disclosed
US-20110019307-A1 METHOD FOR PRODUCING MAGNETIC RECORDING MEDIUM, MAGNETIC RECORDING MEDIUM AND MAGNETIC RECORDING/REPRODUCING APPARATUS SHOWA DENKO K.K. (JP) 2011-01-27 US disclosed
US-20100316889-A1 CURABLE COMPOSITION FOR TRANSFER MATERIALS AND METHOD FOR FORMING MICROPATTERN USING THE CURABLE COMPOSITION SHOWA DENKO K.K. (JP) 2010-12-16 US disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed