SCHEMBL19547985

SCHEMBL19547985

C=C[Si](C)(C)Oc1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
RELA Q04206 1/20 0.38
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TEAD4 Q15561 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1060011 0.91 ALDH1A1 (0.32) CYP3A4TSHRALDH1A1CA1CA2
SCHEMBL2767798 0.81 TDP1 (0.43) KMT2AMEN1RELANPC1RAB9A
SCHEMBL8150674 0.80 CA4 (0.39) KMT2AMEN1TSHRALDH1A1
SCHEMBL21086727 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL18109181 0.75 TRPA1 (0.53) KMT2AMEN1RELANPC1RAB9A
SCHEMBL10148991 0.75 TRPA1 (0.53) KMT2AMEN1RELANPC1RAB9A
SCHEMBL1060422 0.74 ALDH1A1 (0.33) ACHEKMT2AMEN1CYP3A4TSHR
SCHEMBL3873409 0.74 ACHE (0.50) ACHEKMT2AMEN1RELANPC1
SCHEMBL3871449 0.74 ACHE (0.50) ACHEKMT2AMEN1RELANPC1
SCHEMBL2016960 0.74 ACHE (0.50) ACHEKMT2AMEN1RELANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257685-B1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME FUJIFILM CORP (JP) 2020-03-04 EP disclosed
US-10022998-B2 Planographic printing plate precursor, method of producing same, and printing method using same FUJIFILM CORPORATION (JP) 2018-07-17 US disclosed
EP-3257685-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME Fujifilm Corporation (JP) 2017-12-20 EP disclosed
US-20170320350-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND PRINTING METHOD USING SAME FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed