Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794391 | 0.95 | ADRB2 (0.60) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL10604425 | 0.91 | ADRB2 (0.52) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL10604416 | 0.90 | ADRB2 (0.51) | ADRB2CTSLCTSKLMNANAAA | |
| SCHEMBL10607231 | 0.88 | NAAA (0.52) | ADRB2CTSLCTSKNAAACETP | |
| SCHEMBL10607221 | 0.87 | ADRB2 (0.57) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL3645452 | 0.83 | ADRB2 (0.53) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL28022532 | 0.82 | ADRB2 (0.47) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL1186102 | 0.81 | ADRB2 (0.57) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL18314645 | 0.80 | ADRB2 (0.52) | ADRB2CTSLCTSKLMNAHSD17B10 | |
| SCHEMBL10610238 | 0.79 | ADRB2 (0.76) | ADRB2CTSLCTSKLMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182872-B1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0182872-A4 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0182872-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4570011-A | PYROLYSIS OF AN ORTHO ALKYL HALOMETHYL AROMATIC HYDROCARBON IN AN INERT | THE DOW CHEMICAL COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| WO-1985005355-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1985-12-05 | — | — | WO | disclosed |