Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604253 | 0.82 | ADRB2 (0.55) | ADRB2CTSLHSD17B10CTSKLMNA | |
| SCHEMBL10604425 | 0.80 | ADRB2 (0.52) | ADRB2CTSLHSD17B10CTSKLMNA | |
| SCHEMBL1187191 | 0.79 | ADRB2 (0.49) | ADRB2CTSLHSD17B10CTSKSMN1; SMN2 | |
| SCHEMBL10607221 | 0.79 | ADRB2 (0.57) | ADRB2CTSLHSD17B10CTSKLMNA | |
| SCHEMBL10604416 | 0.79 | ADRB2 (0.51) | ADRB2CTSLCTSKLMNA | |
| SCHEMBL27794391 | 0.78 | ADRB2 (0.60) | ADRB2CTSLHSD17B10CTSKLMNA | |
| SCHEMBL10607231 | 0.77 | NAAA (0.52) | ADRB2CTSLCTSK | |
| SCHEMBL3645452 | 0.75 | ADRB2 (0.53) | ADRB2CTSLHSD17B10CTSKSMN1; SMN2 | |
| SCHEMBL1186102 | 0.73 | ADRB2 (0.57) | ADRB2CTSLHSD17B10CTSKSMN1; SMN2 | |
| SCHEMBL18314645 | 0.73 | ADRB2 (0.52) | ADRB2CTSLHSD17B10CTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102344457-B | Spirocyclic aminoquinolones as GSK-3 inhibitors | KYORIN SEIYAKU KK | 2015-07-22 | — | — | CN | disclosed |