SCHEMBL10604259

SCHEMBL10604259

CCCCC(=O)CC(=O)Nc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.61
SOAT1 P35610 1/20 0.61
ALDH1A1 P00352 5/20 0.60
MAPT P10636 2/20 0.58
HPGD P15428 1/20 0.58
GAA P10253 2/20 0.57
ICMT O60725 1/20 0.57
ALB P02768 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
HDAC3 O15379 6/20 0.57
HDAC1 Q13547 6/20 0.57
HDAC2 Q92769 6/20 0.57
HDAC4 P56524 5/20 0.57
HDAC7 Q8WUI4 5/20 0.57
HDAC10 Q969S8 5/20 0.57
HDAC11 Q96DB2 5/20 0.57
HDAC8 Q9BY41 5/20 0.57
HDAC6 Q9UBN7 5/20 0.57
HDAC9 Q9UKV0 5/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630267 0.95 SOAT2 (0.68) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL13678963 0.93 SOAT2 (0.71) SOAT2SOAT1ALDH1A1ICMTALB
SCHEMBL1114242 0.89 MAPT (0.67) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL2183716 0.87 ALDH1A1 (0.76) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL11660177 0.86 ALDH1A1 (0.73) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL10629791 0.85 ALDH1A1 (0.60) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL13997215 0.84 L3MBTL1 (0.59) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL1897242 0.82 SOAT2 (0.79) SOAT2SOAT1ALDH1A1MAPTHPGD
SCHEMBL5804865 0.82 MAPT (0.65) ALDH1A1MAPTHPGDGAAHDAC3
SCHEMBL9479632 0.81 MAPT (0.81) SOAT2SOAT1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62249970-A None JP disclosed
CN-113897631-B Method for electrochemical synthesis of pyridin-2-one derivatives 昆明学院 2023-05-09 CN disclosed
CN-113897631-A Method for electrochemically synthesizing pyridine-2-one derivatives 昆明学院 2022-01-07 CN disclosed
EP-0114059-B1 METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-06-14 EP disclosed
JP-S62249970-A PRODUCTION OF PYRIDONE-3-CARBOXAMIDE COMPOUND DAICEL CHEM IND LTD 1987-10-30 JP disclosed
EP-0083690-B1 POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE AND PROCESS FOR PREPARING POLYIMIDE FROM THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-03-12 EP disclosed
US-4515915-A Polyamide acid composition for preparing polyimide KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-05-07 US disclosed
EP-0114059-A2 Method of preparing a polyamide acid composition for preparing polyimide KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-25 EP disclosed
US-4454276-A POT LIFE EXTENDING AGENT Kanegafuchi Chkagaku Kogyo Kabushiki Kaisha (JP) 1984-06-12 US disclosed