Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604259 | 0.89 | SOAT2 (0.61) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| SCHEMBL10630267 | 0.88 | SOAT2 (0.68) | MAPTALDH1A1HPGDSOAT2SOAT1 | |
| SCHEMBL9888 | 0.86 | ALDH1A1 (0.86) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| SCHEMBL13678963 | 0.86 | SOAT2 (0.71) | ALDH1A1HTTSOAT2SOAT1ICMT | |
| Hydrochloric Acid SCHEMBL23062930 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| Iodide SCHEMBL7927461 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| Bromide SCHEMBL28587932 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| Fluoride SCHEMBL27839088 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| SCHEMBL11658250 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HPGDCYP2C19RECQL | |
| SCHEMBL5804865 | 0.85 | MAPT (0.65) | MAPTALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397241-A | Eco-friendly aftertreatment method of 4-methyl-3-oxo-N-phenylvaleramide | 杨锋 | 2017-02-15 | — | — | CN | disclosed |
| CN-106008251-A | Preparation method of 2-benzylidene isobutyryl acetanilide | 河南豫辰药业股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| EP-2279167-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-FLUORO-ALPHA-Ý2-METHYL -1-OXOPROPYL¨-GAMMA-OXO-N-ß-DIPHENYLBENZENEBUTANAMIDE AND PRODUCTS THEREFROM | Arch Pharmalabs Limited (IN) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009144736-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-FLUORO-ALPHA-[2-METHYL -1-OXOPROPYL]-GAMMA-OXO-N-ß-DIPHENYLBENZENEBUTANAMIDE AND PRODUCTS THEREFROM | ARCH PHARMALABS LIMITED (IN) | 2009-12-03 | — | — | WO | disclosed |
| US-5155251-A | Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-4886546-A | Pyrone-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4739083-A | REACTING 1,3-DIOXAN-4-ONE WITH (AMINE OR IMINE) SUBSTITUTED AMIDE | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0083690-B1 | POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE AND PROCESS FOR PREPARING POLYIMIDE FROM THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4454276-A | POT LIFE EXTENDING AGENT | Kanegafuchi Chkagaku Kogyo Kabushiki Kaisha (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0083690-A1 | Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4305833-A | Lubricating oils containing acetoacetanilides as antioxidants | UOP INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4014679-A | HERBICIDES | ROUSSEL-UCLAF (FR) | 1977-03-29 | — | — | US | disclosed |