Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | SHBG | P04278 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605039 | 0.84 | SHBG (0.71) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL11022317 | 0.77 | CYP19A1 (0.56) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL11020428 | 0.77 | AR (0.61) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL8209314 | 0.76 | CYP19A1 (1.00) | CYP19A1SHBGLMNASMN1; SMN2TSHR | |
| SCHEMBL7736116 | 0.76 | CYP19A1 (1.00) | CYP19A1SHBGLMNASMN1; SMN2TSHR | |
| SCHEMBL7736120 | 0.76 | CYP19A1 (1.00) | CYP19A1SHBGLMNASMN1; SMN2TSHR | |
| SCHEMBL10603375 | 0.76 | LMNA (0.71) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL10603160 | 0.76 | LMNA (0.71) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL9640298 | 0.74 | SMN1; SMN2 (0.71) | CYP19A1NR3C1SHBGCYP2C19MEN1 | |
| SCHEMBL11021243 | 0.74 | CYP3A4 (0.73) | CYP19A1NR3C1SHBGMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152429-B1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1989-10-11 | — | — | EP | disclosed |