Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 7/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | AR | P10275 | 2/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.69 |
| ▸ | BLM | P54132 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605063 | 0.84 | CYP19A1 (0.60) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL11152514 | 0.84 | LMNA (0.92) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL12417537 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL24475 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL7604035 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL780055 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL606819 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL16691330 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL16864523 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 | |
| Ethisterone SCHEMBL14433089 | 0.83 | LMNA (1.00) | SHBGLMNASMN1; SMN2TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152429-B1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1989-10-11 | — | — | EP | claimed |
| EP-0152429-A4 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-12-05 | — | — | EP | claimed |
| EP-0152429-A1 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-08-28 | — | — | EP | claimed |
| US-4512986-A | FERTILITY CONTROL | RESEARCH TRIANGLE INSTITUTE (US) | 1985-04-23 | — | — | US | claimed |
| WO-1985000609-A1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1985-02-14 | — | — | WO | claimed |
| EP-0152429-B1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1989-10-11 | — | — | EP | disclosed |
| EP-0152429-A4 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-12-05 | — | — | EP | disclosed |
| EP-0152429-A1 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4512986-A | FERTILITY CONTROL | RESEARCH TRIANGLE INSTITUTE (US) | 1985-04-23 | — | — | US | disclosed |
| WO-1985000609-A1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1985-02-14 | — | — | WO | disclosed |