Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447491 | 0.91 | REN (0.51) | RENCTSSCTSK | |
| SCHEMBL10444184 | 0.88 | REN (0.53) | RENCTSSCTSK | |
| SCHEMBL10444182 | 0.88 | REN (0.53) | RENCTSSCTSK | |
| SCHEMBL9358862 | 0.87 | CTSS (0.50) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7274022 | 0.87 | CTSS (0.50) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7274017 | 0.87 | CTSS (0.50) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7492742 | 0.87 | REN (0.48) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL10609342 | 0.82 | REN (0.46) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7430523 | 0.82 | CTSS (0.52) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7360557 | 0.82 | CTSS (0.44) | RENCTSSCTSKCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |