Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604101 | 0.89 | RAB9A (0.57) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL10703352 | 0.86 | KMT2A (0.53) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL13774579 | 0.86 | MEN1 (0.63) | HTTJAK2JAK1TYK2NOD2 | |
| Diflubenzuron SCHEMBL42416 | 0.86 | RAB9A (0.59) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL7605886 | 0.86 | KMT2A (0.59) | MAOAMAOBHTTJAK2JAK1 | |
| SCHEMBL11244486 | 0.86 | RAB9A (0.55) | HTTJAK2JAK1TYK2NOD2 | |
| Diflubenzuron SCHEMBL18837607 | 0.86 | RAB9A (0.59) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL9737605 | 0.84 | KMT2A (0.51) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL10704217 | 0.84 | NPC1 (0.53) | HTTJAK2JAK1TYK2NOD2 | |
| SCHEMBL9324631 | 0.83 | RAB9A (0.57) | HTTJAK2JAK1TYK2NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136745-B1 | BENZOYL UREA DERIVATIVES HAVING ANTI-TUMOR ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-06-07 | — | — | EP | claimed |
| EP-0193249-A2 | Benzoyl urea derivatives having ati-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-09-03 | — | — | EP | claimed |
| EP-0136745-A2 | Benzoyl urea derivatives having anti-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-04-10 | — | — | EP | claimed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | claimed |
| CN-111718285-A | Application of benzoylurea compound containing carbonic diester group structure as bactericide | 天津农学院 | 2020-09-29 | — | — | CN | disclosed |
| EP-0136745-B1 | BENZOYL UREA DERIVATIVES HAVING ANTI-TUMOR ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-06-07 | — | — | EP | disclosed |
| EP-0193249-A2 | Benzoyl urea derivatives having ati-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0136745-A2 | Benzoyl urea derivatives having anti-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-04-10 | — | — | EP | disclosed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | disclosed |