Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604101 | 0.87 | RAB9A (0.57) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL678422 | 0.87 | JAK2 (0.65) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL10608014 | 0.86 | MAOA (0.51) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL10703352 | 0.84 | KMT2A (0.53) | RAB9AMAPTKMT2AMEN1JAK2 | |
| Diflubenzuron SCHEMBL18837607 | 0.84 | RAB9A (0.59) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL7605886 | 0.84 | KMT2A (0.59) | RAB9AMAPTKMT2AMEN1JAK2 | |
| Diflubenzuron SCHEMBL42416 | 0.84 | RAB9A (0.59) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL13774579 | 0.84 | MEN1 (0.63) | RAB9AMAPTKMT2AMEN1JAK2 | |
| SCHEMBL7605796 | 0.84 | MEN1 (0.50) | RAB9AMAPTKMT2AMEN1JAK2 | |
| Diflubenzuron SCHEMBL8729691 | 0.84 | NPC1 (0.56) | RAB9AMAPTKMT2AMEN1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |