SCHEMBL7604101

SCHEMBL7604101

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(F)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.57
NPC1 O15118 5/20 0.57
HTT P42858 2/20 0.57
POLB P06746 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 1/20 0.54
JAK2 O60674 1/20 0.53
JAK1 P23458 1/20 0.53
TYK2 P29597 1/20 0.53
NOD2 Q9HC29 1/20 0.53
KMT2A Q03164 7/20 0.52
MEN1 O00255 6/20 0.52
CDK1 P06493 1/20 0.52
CCNB1 P14635 1/20 0.52
CCNA2 P20248 1/20 0.52
CDK2 P24941 1/20 0.52
CCNA1 P78396 1/20 0.52
ATM Q13315 1/20 0.51
PKM P14618 1/20 0.51
GAA P10253 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10704217 0.95 NPC1 (0.53) RAB9ANPC1HTTPOLBSMN1; SMN2
SCHEMBL10608014 0.89 MAOA (0.51) RAB9ANPC1HTTPOLBSMN1; SMN2
SCHEMBL10703352 0.87 KMT2A (0.53) RAB9ANPC1HTTPOLBSMN1; SMN2
SCHEMBL11244486 0.87 RAB9A (0.55) RAB9ANPC1HTTPOLBLMNA
SCHEMBL13774579 0.87 MEN1 (0.63) RAB9ANPC1HTTSMN1; SMN2LMNA
Diflubenzuron SCHEMBL42416 0.87 RAB9A (0.59) RAB9ANPC1HTTJAK2JAK1
Diflubenzuron SCHEMBL18837607 0.87 RAB9A (0.59) RAB9ANPC1HTTJAK2JAK1
SCHEMBL7605886 0.87 KMT2A (0.59) RAB9ANPC1HTTSMN1; SMN2LMNA
SCHEMBL30739821 0.86 JAK2 (0.69) RAB9ANPC1HTTPOLBSMN1; SMN2
SCHEMBL9737605 0.86 KMT2A (0.51) RAB9ANPC1HTTPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-6057370-A APPLYING TO THE FOLIAGE OF SAID GENETICALLY ALTERED COTTON PLANT AN ENHANCED PESTICIDALLY ACTIVE AMOUNT OF A SUBSTITUTED BENZOYL UREA MACDERMID AGRICULTURAL SOLUTIONS, INC. 2000-05-02 US disclosed
US-5142064-A Larvicides has benzoyl or thiobenzoyl group DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1992-08-25 US disclosed
US-4920135-A NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1990-04-24 US disclosed
US-4833151-A INTERFERES WITH METAMORPHOSES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-05-23 US disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 RAB9A 1813/4885NPC1 1857/4885HTT 3044/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 RAB9A 1813/4885NPC1 1857/4885HTT 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.