Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604101 | 0.86 | RAB9A (0.57) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL10608014 | 0.84 | MAOA (0.51) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL10494618 | 0.84 | MAPT (0.51) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL10494620 | 0.84 | MAPT (0.51) | KMT2AATMNPC1RAB9AMEN1 | |
| Diflubenzuron SCHEMBL42416 | 0.83 | RAB9A (0.59) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL7605886 | 0.83 | KMT2A (0.59) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL10703352 | 0.83 | KMT2A (0.53) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL11244486 | 0.83 | RAB9A (0.55) | KMT2AATMNPC1RAB9AMEN1 | |
| Diflubenzuron SCHEMBL18837607 | 0.83 | RAB9A (0.59) | KMT2AATMNPC1RAB9AMEN1 | |
| SCHEMBL13774579 | 0.83 | MEN1 (0.63) | KMT2AATMNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |