Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138442 | 0.74 | CA9 (0.42) | KMT2AMAPTALDH1A1POLBHTT | |
| SCHEMBL17666797 | 0.73 | KAT6A (0.37) | KMT2AGAAMAPTHTTLMNA | |
| SCHEMBL10608062 | 0.73 | MEN1 (0.39) | KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL15988245 | 0.73 | ALDH1A1 (0.40) | KMT2AGAAMAPTALDH1A1POLB | |
| SCHEMBL9615904 | 0.72 | RORC (0.39) | KMT2AGAAMAPTALDH1A1POLB | |
| SCHEMBL9724989 | 0.72 | RORC (0.39) | KMT2AGAAMAPTALDH1A1POLB | |
| SCHEMBL10560063 | 0.71 | TSHR (0.48) | KMT2AGAAMAPTALDH1A1POLB | |
| SCHEMBL20583291 | 0.71 | POLB (0.32) | KMT2AGAAALDH1A1POLBHTT | |
| SCHEMBL23357600 | 0.70 | CYP1A2 (0.41) | KMT2AMAPTALDH1A1POLBLMNA | |
| SCHEMBL9614144 | 0.70 | MEP1B (0.36) | KMT2AGAAMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4526893-A | Pharmaceuticals | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | disclosed |