Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606178 | 0.93 | HDAC3 (0.50) | MAOAMAOBMAPTRXFP1IGF1R | |
| SCHEMBL4514776 | 0.83 | TDP1 (0.52) | MAOAMAOBALOX15HDAC3MAPK1 | |
| SCHEMBL17236295 | 0.81 | SIGMAR1 (0.50) | MAOAMAOBMAPTRXFP1IGF1R | |
| SCHEMBL451456 | 0.80 | MAOA (0.74) | MAOAMAOBMAPTRXFP1ALOX15 | |
| SCHEMBL4520474 | 0.78 | MAOB (0.57) | MAOAMAOBSIGMAR1TDP1NOS1 | |
| SCHEMBL707928 | 0.77 | MAOA (0.52) | MAOAMAOBMAPTRXFP1SIGMAR1 | |
| SCHEMBL707816 | 0.77 | MAOA (0.52) | MAOAMAOBMAPTRXFP1IGF1R | |
| SCHEMBL705290 | 0.77 | MAOA (0.52) | MAOAMAOBMAPTRXFP1SIGMAR1 | |
| SCHEMBL2803699 | 0.77 | MAOA (0.52) | MAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL8085946 | 0.77 | SIGMAR1 (0.71) | MAOAMAOBMAPTRXFP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139234-B1 | RESIN COMPOSITION | KABUSHIKI KAISHA TOSHIBA (JP) | 1989-11-29 | — | — | EP | disclosed |
| US-4599155-A | POLYORTHOESTERS;SHRINKAGE INHIBITION;NONCRACKING;COATINGS | KABUSHIKI KAISHA TOSHIBA (JP) | 1986-07-08 | — | — | US | disclosed |
| EP-0139234-A2 | Resin composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-05-02 | — | — | EP | disclosed |