SCHEMBL2803699

SCHEMBL2803699

C[SiH](C)CCCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SIGMAR1 Q99720 8/20 0.50
MAOB P27338 2/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31154202 0.98 SIGMAR1 (0.53) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL28564556 0.98 SIGMAR1 (0.53) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL476048 0.93 L3MBTL1 (0.48) MAOAL3MBTL1SIGMAR1MAOBMEN1
SCHEMBL476138 0.83 TP53 (0.50) MAOAL3MBTL1MAOB
SCHEMBL29011093 0.83 L3MBTL1 (0.48) MAOAL3MBTL1SIGMAR1MAOBMEN1
SCHEMBL17236295 0.81 SIGMAR1 (0.50) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL451456 0.80 MAOA (0.74) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL707928 0.77 MAOA (0.52) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL705290 0.77 MAOA (0.52) MAOAL3MBTL1SIGMAR1MAOB
SCHEMBL10608209 0.77 MAOA (0.52) MAOAL3MBTL1SIGMAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
CN-115128190-A Method for measuring modification rate of polymer 株式会社LG化学 2022-09-30 CN disclosed
US-8785574-B2 Bridged metallocene compound, olefin polymerization catalyst containing the same, and ethylene polymer obtained with the catalyst MITSUI CHEMICALS, INC. (JP) 2014-07-22 US disclosed
US-20140114031-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST PRIME POLYMER CO., LTD. (JP) 2014-04-24 US disclosed
EP-2218725-B1 BRIDGED METALLOCENE OLEFIN POLYMERIZATION CATALYST AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST MITSUI CHEMICALS INC (JP) 2013-10-23 EP disclosed
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST MITSUI CHEMICALS, INC. 2010-11-18 US disclosed
EP-2218725-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST Mitsui Chemicals, Inc. (JP) 2010-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST CAD, ENDOD1, CCT7 MAOA 1964/4885L3MBTL1 972/4885SIGMAR1 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.